The best Side of megatomi.com
Our new Apparent+ tissue clearing procedure is the one approach that delipidates samples with no modify in morphology and with nominal impact on structural integrity.Megatome is really a vibrating microtome designed to portion a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome permits large-throughput tissue sectioning with uniform surface profile, and small tissue injury and information decline.
Antibodies could choose weeks to diffuse by only a few millimeters of tissue, that has a steep labeling gradient from surface to Main.
Megatome is designed for precision: the blade vibrates at a higher frequency and larger amplitude vary than other microtomes, and includes a exceptional deflection Manage system.
SE makes use of a rotational electric powered area to disperse highly electromobile molecules (for instance antibodies or surfactant micelles) in the course of a porous sample with out harming electrically charged buildings within the tissue. This enables 2-four working day clearing of intact organs,
Our preformulated EasyIndex megatomi.com Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them fully transparent. This enables mild penetration to the sample and assures the acquisition of significant-resolution, in-concentration graphic info.
Megatome is really a novel microtome that allows for top-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimum tissue damage and knowledge decline.
It’s time and energy to improve your microtome to Megatome. With exact substantial-frequency slicing for an unmatched range of sample measurements and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for various applications.
Entirely delipidate whole mouse brains or comparably sized samples in only one working day with SmartBatch+, or in one 7 days with our passive clearing package.
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Leverage the Distinct+ tissue clearing technique, together with eFLASH and patented stochastic electrotransport technologies, to quickly distinct and label entire organs. Important highlights and attributes consist of:
Our novel SHIELD tissue preservation technique forms intramolecular bonds using polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.